Lesser-known Symptoms Often Missed During Hormonal Changes

Recent research reveals that women may experience several unexpected symptoms during perimenopause beyond the classic hot flashes and menstrual irregularity. Many symptoms are not widely recognized as being linked to hormonal changes of perimenopause, which are often overlooked by doctors, yet have a significant impact on quality of life during perimenopause.  


What are these lesser-known perimenopause symptoms?

  • Frequent or urgent urination: Bladder symptoms, including increased frequency and urgency, occur via estrogen's effects on the lower urinary tract. 

  • Digestive changes: Indigestion, bloating, and even new allergies can develop, reflecting estrogen's widespread effects. 

  • Dizziness: Sudden episodes of dizziness or vertigo may emerge without an obvious cause. 

  • Hair loss and brittle nails: Sudden changes in hair texture, unexpected shedding, and weak or peeling nails can occur. 

  • Tinnitus and burning mouth syndrome: Auditory changes or unusual sensations in the mouth and tongue are documented but rarely discussed. 

  • Brain fog, forgetfulness, and cognitive issues: Difficulty concentrating, memory lapses, and reduced mental clarity are frequently reported, often surprising women who expect mainly physical changes. 

  • Heart palpitations: Increased awareness of heartbeats or irregular rhythms is linked to hormonal fluctuations. 

  • New or worsening anxiety and depression: Emotional symptoms may become more pronounced or appear for the first time, even in individuals with no prior history of mood disorders. 

  • Joint pain and muscle aches: Unexplained aches, pains, or stiffness in the body are becoming increasingly common, sometimes mimicking the early signs of autoimmune or rheumatologic issues. 

  • Sensory disturbances — including changes in taste, increased body odor, tingling in the extremities, and even electric shock sensations are reported more frequently in new research.


Why This Matters

These symptoms reflect the broad distribution of estrogen receptors throughout the body, not only in our reproductive system, impacting neurological, cardiovascular, musculoskeletal, urogenital, and integumentary systems. Thus, further clarifying the impact of hormones and the importance of monitoring them.  

Many women and clinicians may miss or misattribute these symptoms, highlighting the importance of increased awareness around perimenopause. Women in their 30s and 40s may experience these symptoms, often many years before menopause, and a lack of awareness remains prevalent even among clinicians. Increasing recognition of this diverse symptom spectrum is critical to optimizing care for women in perimenopause and helping prepare them towards a smooth transition into post-menopause.  


Ready to Feel More Like Yourself Again?

You don’t have to go through this alone. Let’s work together in a Hormone Strategy Session to build a personalized plan that helps you feel steady, focused, and in control during this transition.

Be well,
Dr. Talina Hermann

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What Every Woman in her 40s Should Know

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How Perimenopause Affects our Immune System